CNS depression
- Suppresses arousal and/or respiratory drive
- Sedatives, opioids + alcohol can synergize
- Falls, impaired driving + overdose risk rise
- Respiratory disease and older age magnify danger
- “Sedation” may understate severe combinations
Interaction at a glance
- Suppresses arousal and/or respiratory drive
Clinical consequence
- Suppresses arousal and/or respiratory drive
- Sedatives, opioids + alcohol can synergize
Who is at greatest risk
- Respiratory disease and older age magnify danger
- “Sedation” may understate severe combinations
Clinical consequence / modifiers
- Falls, impaired driving + overdose risk rise
Self-check
- What patient factors magnify CNS-depressant danger?
Respiratory disease and older age. - Key clinical effect of CNS depression?
Falls, impaired driving + overdose risk rise.
Drugs in this interaction (150)
All interaction examples · Open CNS depression in the interactive console ↗