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Endomorphins

endogenous

What it isEndogenous peptides with the highest mu selectivity known.

Why this oneTheir selectivity is the benchmark against which synthetic mu ligands are compared.

What limits itNo drug reproduces their selectivity, which is part of why opioid analgesia remains inseparable from respiratory depression.

NO BOXED WARNINGS

Principal riskEndogenous or dietary; no boxed warning applies

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

Mechanism of action: Endomorphins ballicule

Endomorphins ballicule: receptor binding, kinetics and half-life diagram

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