Xylazine
veterinary
“Xyla Tranq”
Known as “Tranq”, cut with fentanyl
Xyla the Horse → horse tranquilizer
Orange plus signs → α2 agonist
What it isAlpha-2 agonist veterinary sedative; a common adulterant of illicit fentanyl.
Why this oneIts recognition matters because it explains sedation that naloxone does not reverse.
What limits it⚑ Naloxone does NOT reverse it, and it causes severe necrotic ulcers at and away from injection sites. No approved human use.
Used for
- veterinary sedation (now a common adulterant in the illicit fentanyl supply)
NO BOXED WARNINGS
Principal risk⚑ Naloxone does NOT reverse it, and it causes severe necrotic ulcers at and away from injection
Classes and tags
Open Xylazine in the interactive console ↗
Self-check
- Does naloxone reverse xylazine sedation?
No. - Where can xylazine-associated necrotic ulcers occur?
At and away from injection sites.