Apigenin
flavonoid
What it isDietary flavonoid with weak benzodiazepine-site activity, found in chamomile.
Why this oneProposed basis for chamomile’s mild calming effect.
What limits itWeak CYP inhibition means supplement doses can interact; clinical evidence is thin.
Used for
- dietary flavonoid (no approved indication)
- sedation/anxiolysis (chamomile constituent; limited evidence)
NO BOXED WARNINGS
Principal riskWeak CYP inhibition at supplement doses
Classes and tags
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Self-check
- What is proposed to underlie chamomile’s mild calming effect?
Apigenin’s weak benzodiazepine-site activity. - How strong is clinical evidence for apigenin?
Thin.