in FIORICET
What it isBarbiturate combined with acetaminophen or aspirin and caffeine; tension and mixed headache.
Why this oneIt relieves refractory headache when simple analgesics have failed.
What limits itMedication-overuse headache develops quickly, and barbiturate dependence and withdrawal follow regular use. Most headache guidelines advise against it.
NO BOXED WARNINGS
Principal riskMedication-overuse headache and barbiturate dependence

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