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THDOC

allotetrahydro- DOC

What it isTetrahydrodeoxycorticosterone, an endogenous neurosteroid and GABA-A positive modulator.

Why this oneIt rises with stress and may be a homeostatic brake on the stress response.

What limits itIt acts at extrasynaptic receptors that benzodiazepines cannot reach, like allopregnanolone.

NO BOXED WARNINGS

Principal riskIt acts at extrasynaptic receptors that benzodiazepines cannot reach, like allopregnanolone

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

Mechanism of action: THDOC ballicule

THDOC ballicule: receptor binding, kinetics and half-life diagram

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