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Beta-endorphin

β-END

What it isEndogenous opioid peptide acting at mu and delta receptors.

Why this oneIt is the endogenous ligand whose system every opioid drug engages.

What limits itIts release during stress and exercise is why opioid antagonists blunt exercise-induced analgesia.

NO BOXED WARNINGS

Principal riskEndogenous or dietary; no boxed warning applies

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

Mechanism of action: Beta-endorphin ballicule

Beta-endorphin ballicule: receptor binding, kinetics and half-life diagram

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