MAOI + not potentially fatal combinations (Gillman)
- This card concerns fatal serotonin toxicity
- These partners are not potent SRIs/releasers
- other interaction risks may still exist
- Examples: nortriptyline, mirtazapine
- Also bupropion, trazodone, atomoxetine
- “Not fatal ST” does NOT mean risk-free
Interaction at a glance
- This card concerns fatal serotonin toxicity
Mechanism
- Examples: nortriptyline, mirtazapine
- Also bupropion, trazodone, atomoxetine
Clinical consequence
- This card concerns fatal serotonin toxicity
Who is at greatest risk
- These partners are not potent SRIs/releasers
- other interaction risks may still exist
- “Not fatal ST” does NOT mean risk-free
Self-check
- What is the main clinical risk of MAOI + not potentially fatal combinations (Gillman)?
This card concerns fatal serotonin toxicity.
Drugs in this interaction (139)
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