Lysergic acid diethylamide
LSD
What it isSerotonergic psychedelic and potent 5-HT2A agonist; investigational for anxiety.
Why this oneA single supervised dose has produced sustained anxiolytic effect in trials, which chronic dosing does not require.
What limits itTwelve-hour duration demands prolonged supervision. Not approved; contraindicated in psychosis risk.
Used for
- anxiety/depression (investigational; not approved)
- generalized anxiety disorder (phase 3; breakthrough designation)
NO BOXED WARNINGS
Principal riskTwelve-hour duration demands prolonged supervision
Classes and tags
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Self-check
- Why does LSD require prolonged supervision?
Its twelve-hour duration. - Is LSD approved for anxiety?
No; investigational.