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Reboxetine

EDRONAX

What it isSelective norepinephrine reuptake inhibitor; depression outside the US.

Why this onePurely noradrenergic, so sexual dysfunction is uncommon.

What limits itEfficacy was disputed after unpublished trials were released, and it was never US-approved. Insomnia, dry mouth and urinary hesitancy.

NO BOXED WARNINGS

Principal riskDisputed efficacy; never US-approved

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

Mechanism of action: Reboxetine ballicule

Reboxetine ballicule: receptor binding, kinetics and half-life diagram

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