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Nordiazepam

desmethyldiazepam

What it isDesmethyldiazepam — the shared active metabolite of diazepam, chlordiazepoxide, clorazepate, and halazepam.

Why it mattersIt is why those benzodiazepines behave as one very-long-acting family: whatever the parent, days-long nordiazepam accumulates underneath.

What it changesAccumulation is the clinical point — hangover sedation, falls in the elderly, and slow self-tapering washout after discontinuation.

NO BOXED WARNINGS

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

Active metabolites

Mechanism of action: Nordiazepam ballicule

Nordiazepam ballicule: receptor binding, kinetics and half-life diagram

Open Nordiazepam in the interactive console ↗