Methylene blue
PROVAYBLUE
What it isRedox antidote that reduces methemoglobin and also inhibits MAO-A/B; methemoglobinemia and ifosfamide encephalopathy.
Why this oneIt is the specific antidote for methemoglobinemia and acts rapidly.
What limits it⚑ Its potent MAO inhibition can cause serotonin syndrome with serotonergic drugs. It can cause hemolysis in G6PD deficiency.
NO BOXED WARNINGS
Principal riskIt is a potent MAOI — serotonin syndrome with SSRIs
Classes and tags
Clinical profile
Mechanism of action: Methylene blue ballicule
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Memory aids: mascots and interaction avatars
Mao Zedong → monoamine oxidase (MAO) inhibitor