Antimuscarinic burden
- Antimuscarinic effects are cumulative
- Dry mouth, constipation + urinary retention
- Cognitive impairment/delirium can emerge
- Older adults and dementia are most vulnerable
- Count the whole regimen—not one drug
Interaction at a glance
- Antimuscarinic effects are cumulative
Mechanism
- Antimuscarinic effects are cumulative
- Dry mouth, constipation + urinary retention
Mechanism / modifiers
- Cognitive impairment/delirium can emerge
Mechanism / exceptions
- Older adults and dementia are most vulnerable
- Count the whole regimen—not one drug
Self-check
- How do the effects represented by Antimuscarinic burden combine?
Antimuscarinic effects are cumulative.
Drugs in this interaction (56)
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