Bleeding risk

Interaction at a glance

• Drug increases clinically meaningful bleeding risk

Mechanism

• Stacking multiple hemostatic drugs is important
• Severity ranges from bruising to major hemorrhage

Clinical consequence

• Drug increases clinically meaningful bleeding risk

Who is at greatest risk

• Mechanisms may be anticoagulant or platelet effects
• GI lesions/NSAIDs/anticoagulants can magnify risk

Self-check

• What can magnify a drug’s bleeding risk?
  GI lesions, NSAIDs and anticoagulants.
• What is the severity range of drug-related bleeding?
  Bruising to major hemorrhage.

Drugs in this interaction (59)

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