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Aspirin

ASA

What it isIrreversible COX-1 and COX-2 inhibitor; secondary cardiovascular prevention, acute coronary syndrome and stroke.

Why this oneIts irreversible platelet effect persists for each platelet's lifespan, distinguishing it from other NSAIDs.

What limits itGI bleeding limits use; primary prevention rarely justifies it. Avoid in viral illness in children; ibuprofen taken first blunts platelet effect.

FDA-approved for

FDA label

FDA dosingPopulationStartTargetMax
Not stated in fetched sections (OTC analgesic/antipyretic label — Uses/Purpose section absent)Adults & children ≥12 yr4 tablets q4h PRN4–8 tablets q4h PRN while symptoms last48 tablets/24 h

Renal Undefined

Hepatic Undefined

Dose expressed in tablets only — tablet strength (mg) is not stated in any fetched section.

Instructions

Pregnancy Undefined

Lactation Undefined

NO BOXED WARNINGS

Principal riskGI bleeding, and Reye syndrome in children

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

Mechanism of action: Aspirin ballicule

Aspirin ballicule: receptor binding, kinetics and half-life diagram

Open Aspirin in the interactive console ↗

Memory aids: mascots and interaction avatars

Aspirin (ASA) mascot mnemonic cartoon
““Aspirin’ Echo trainer” / “Asa, the Aspirin’ Bear””
Bear for Bayer
Asa for A.S.A. = Acetylsalicylic acid
Echo Trainer for Ecotrin
Aspirin weak acid avatar
weak acid

Open Aspirin in the interactive console ↗