Myelosuppression
- Suppresses bone-marrow blood-cell production
- Neutropenia, anemia + thrombocytopenia may occur
- Risk often rises with dose/exposure
- Cytotoxic combinations can be cumulative
- CBC monitoring is often required
Interaction at a glance
- Suppresses bone-marrow blood-cell production
Mechanism
- Suppresses bone-marrow blood-cell production
- Neutropenia, anemia + thrombocytopenia may occur
Mechanism / modifiers
- Cytotoxic combinations can be cumulative
Clinical consequence
- Risk often rises with dose/exposure
- CBC monitoring is often required
Self-check
- How does myelosuppression risk often change with dose/exposure?
It rises. - What monitoring is often required for myelosuppressive drugs?
CBC.
Drugs in this interaction (64)
All interaction examples · Open Myelosuppression in the interactive console ↗