Antipsychotics

Class at a glance

• Treat psychosis; many also treat mood illness

Practical pearls

• SGAs differ greatly in metabolic burden
• FGAs often carry more EPS/prolactin burden

Other practical pearls

• D2 signaling is the core shared target

Safety / monitoring

• Clozapine is unique for TRS + suicide risk
• QT, sedation + antimuscarinic effects vary

Self-check

• Which antipsychotic is unique for TRS and suicide risk?
  Clozapine.
• Which signaling pathway is the core shared antipsychotic target?
  D2 signaling.

Drugs in this class (38)

All drug classes · Open Antipsychotics in the interactive console ↗