Nausea/vomiting
- Treat cause + correct dehydration/electrolytes
- Choose antiemetic by mechanism/context
- 5-HT3 antagonists are versatile and nonsedating
- Dopamine/H1/M1 blockers add sedation/EPS/antimuscarinic effects
- Pregnancy, migraine, gastroparesis + chemotherapy differ
- Persistent vomiting needs obstruction/CNS/metabolic evaluation
Use at a glance
- Treat cause + correct dehydration/electrolytes
Practical pearls
- Choose antiemetic by mechanism/context
- 5-HT3 antagonists are versatile and nonsedating
Other practical pearls
- Dopamine/H1/M1 blockers add sedation/EPS/antimuscarinic effects
Treatment options
- Pregnancy, migraine, gastroparesis + chemotherapy differ
- Persistent vomiting needs obstruction/CNS/metabolic evaluation
Self-check
- What should guide antiemetic selection?
Mechanism and context.
- Which antiemetic class is versatile and nonsedating?
5-HT3 antagonists.
Drugs used for this (18)
All clinical uses · Open Nausea/vomiting in the interactive console ↗