Type 2 diabetes mellitus (T2DM)
- Lifestyle + weight management throughout
- ASCVD: GLP-1 RA and/or SGLT2 favored
- Heart failure: prioritize SGLT2 inhibitor
- CKD: SGLT2; add GLP-1 as appropriate
- Obesity: GLP-1/GIP-GLP-1 often favored
- Otherwise metformin remains a common base
- Combine early if far above A1c target
- Catabolic/severe hyperglycemia → insulin
Use at a glance
- Lifestyle + weight management throughout
Practical pearls
- ASCVD: GLP-1 RA and/or SGLT2 favored
- Heart failure: prioritize SGLT2 inhibitor
Other practical pearls
- CKD: SGLT2; add GLP-1 as appropriate
- Obesity: GLP-1/GIP-GLP-1 often favored
- Otherwise metformin remains a common base
Choosing treatment
- Combine early if far above A1c target
- Catabolic/severe hyperglycemia → insulin
Self-check
- What is recommended for Catabolic/severe hyperglycemia in Type 2 diabetes mellitus (T2DM)?
insulin.
Drugs used for this (36)
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