Seizure disorders (focal)
- Many ASMs are effective; tolerability drives selection
- Levetiracetam/lamotrigine are common first choices
- Carbamazepine/oxcarbazepine remain effective options
- After 2 appropriate failures → drug-resistant epilepsy
- Evaluate surgery for focal drug-resistant disease
- Match drug to pregnancy, mood + interaction profile
Use at a glance
- Many ASMs are effective; tolerability drives selection
Treatment options
- Evaluate surgery for focal drug-resistant disease
Other treatment options
- Levetiracetam/lamotrigine are common first choices
- Carbamazepine/oxcarbazepine remain effective options
- After 2 appropriate failures → drug-resistant epilepsy
Treatment sequence
- Match drug to pregnancy, mood + interaction profile
Self-check
- What guides focal-seizure drug choice?
Pregnancy, mood + interaction profile. - What should be evaluated for focal drug-resistant epilepsy?
Surgery.
Drugs used for this (23)
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