Withdrawn from the market (safety)
Ezogabine
POTIGA
What it isKCNQ potassium channel opener; focal seizures. Withdrawn.
Why this oneA mechanism no other antiepileptic used — opening a potassium channel rather than blocking sodium.
What limits itBlue-gray skin and retinal pigment changes ended its marketing.
FDA-approved for
- partial-onset seizures (2011)
⚠ BOXED WARNING
- Retinal abnormalities and potential vision loss
Classes and tags
Clinical profile
Mechanism of action: Ezogabine ballicule
