Diabetes mellitus
- Type 1 requires insulin
- Type 2 therapy is comorbidity- and goal-driven
- GLP-1/GIP-GLP-1 drugs favor weight/ASCVD benefit
- SGLT2 inhibitors favor HF/CKD benefit
- Metformin remains a common low-cost foundation
- Severe/catabolic hyperglycemia may require insulin
Use at a glance
Practical pearls
- Metformin remains a common low-cost foundation
Treatment options
- GLP-1/GIP-GLP-1 drugs favor weight/ASCVD benefit
- SGLT2 inhibitors favor HF/CKD benefit
Other treatment options
- Type 2 therapy is comorbidity- and goal-driven
- Severe/catabolic hyperglycemia may require insulin
Self-check
- Which diabetes type requires insulin?
Type 1.
- Which diabetes drug class favors HF/CKD benefit?
SGLT2 inhibitors.
Drugs used for this (36)
All clinical uses · Open Diabetes mellitus in the interactive console ↗