Constipation
- Identify alarm features + drug/medical causes
- Fiber when intake is low and motility is adequate
- PEG is a common first-line osmotic laxative
- Add stimulant for rescue or combination therapy
- Refractory CIC → secretagogue or prucalopride
- Severe hypomotility requires a more aggressive plan
Use at a glance
- Identify alarm features + drug/medical causes
Escalation / refractory disease
- PEG is a common first-line osmotic laxative
- Refractory CIC → secretagogue or prucalopride
Treatment options
- Add stimulant for rescue or combination therapy
Choosing treatment
- Fiber when intake is low and motility is adequate
- Severe hypomotility requires a more aggressive plan
Self-check
- What treats refractory CIC?
Secretagogue or prucalopride.
- When is fiber suitable for constipation?
Low intake with adequate motility.
Drugs used for this (14)
All clinical uses · Open Constipation in the interactive console ↗