Senna
SENOKOT
What it isPlant-derived anthraquinone laxative activated by colonic bacteria; constipation.
Why this oneUnlike docusate, it reliably promotes bowel movements and is routinely paired with opioids from the start.
What limits itCramping is common. Melanosis coli with chronic use is benign and reversible; evidence does not support the old cathartic-colon fear.
FDA-approved for
- constipation (~1950)
FDA label
Read the full label on DailyMed ↗
| FDA dosing | Population | Start | Target | Max |
|---|---|---|---|---|
| Constipation | Adults & children ≥12 yr | 2 tablets QD-BID | 2 tablets BID | |
| Constipation | Children 6-<12 yr | 1 tablet QD-BID | 1 tablet BID |
Renal Undefined
Hepatic Undefined
Instructions
- Swallow tablet(s) whole with a glass of water; do not crush, break, or chew
- Children under 6 yr: ask a doctor
Pregnancy Undefined
Lactation Undefined
NO BOXED WARNINGS
Principal riskCramping; melanosis coli with chronic use
Classes and tags
Clinical profile
Mechanism of action: Senna ballicule
