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Bisacodyl

DULCOLAX

Pronunciation: bis-AK-oe-dil

Bisacodyl ballicule: receptor binding, kinetics and half-life diagram
Mechanism of action: Bisacodyl ballicule
Bisacodyl DULCOLAX mascot mnemonic cartoon
Visual mnemonic: Bisacodyl mascot
“Dookie laxative Busy coding”

What it isLocally acting colonic laxative; constipation and bowel preparation.

Why this oneReliable onset within six to twelve hours orally, or an hour rectally.

What limits itCramping and electrolyte loss can occur. The enteric coating must not be crushed or taken with antacids.

Bisacodyl molecular structure (skeletal formula)
Molecular structure: Bisacodyl

Bisacodyl prescription history

Animated chart of estimated U.S. prescriptions per year, Constipation meds (1900–2026). Bisacodyl enters in 1955 (estimated).

FDA-approved for

Principal riskCramping and electrolyte loss

Classes and tags

Clinical profile

Therapeutic safety burden1 / 4
Sedation liability0 / 4
Direct muscarinic antagonism0 / 4
Embryofetal risk1 / 4

FDA label

NO BOXED WARNINGS

FDA dosingPopulationStartTargetMax
Occasional constipationAdults & children ≥12 yr1–3 tablets QD1–3 tablets QD3 tablets QD
Occasional constipationChildren 6 to <12 yr1 tablet QD1 tablet QD1 tablet QD

Renal Undefined

Hepatic Undefined

Instructions

Available strengths

Pregnancy Undefined

Lactation Undefined

Cost

Bisacodyl (DULCOLAX)
What pharmacies pay · NADAC 9/30/26 · OTC
Strength#/mogeneric $/moCostPlus
5 mgDR tab30 qd$1.32not offered

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