Hepatotoxicity
- Clinically important liver-injury potential
- Pattern may be hepatocellular or cholestatic
- Risk can be dose-related or idiosyncratic
- Symptoms/LFT monitoring depends on the drug
- Stop urgently for severe injury signals
Interaction at a glance
- Clinically important liver-injury potential
Mechanism
- Clinically important liver-injury potential
Mechanism / modifiers
- Pattern may be hepatocellular or cholestatic
- Stop urgently for severe injury signals
Clinical consequence
- Risk can be dose-related or idiosyncratic
- Symptoms/LFT monitoring depends on the drug
Self-check
- What major clinical effect is associated with Hepatotoxicity?
Risk can be dose-related or idiosyncratic.
Drugs in this interaction (47)
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