Hepatotoxicity
- Clinically important liver-injury potential
- Pattern may be hepatocellular or cholestatic
- Risk can be dose-related or idiosyncratic
- Symptoms/LFT monitoring depends on the drug
- Stop urgently for severe injury signals
Interaction at a glance
- Clinically important liver-injury potential
Mechanism
- Clinically important liver-injury potential
Mechanism / modifiers
- Pattern may be hepatocellular or cholestatic
- Stop urgently for severe injury signals
Clinical consequence
- Risk can be dose-related or idiosyncratic
- Symptoms/LFT monitoring depends on the drug
Self-check
- Key clinical effect of Hepatotoxicity?
Risk can be dose-related or idiosyncratic. - What liver-injury patterns may occur?
Hepatocellular or cholestatic.
Drugs in this interaction (49)
All interaction examples · Open Hepatotoxicity in the interactive console ↗