NSAIDs
- COX inhibition → analgesic/anti-inflammatory
- Acute musculoskeletal/inflammatory pain
- GI ulcer/bleeding + renal injury are key risks
- Can raise BP + worsen edema/heart failure
- Celecoxib: less GI injury; CV/renal risk remains
- Ketorolac: potent, short-term only
- Aspirin is unique for antiplatelet use
- Avoid stacking multiple NSAIDs
Class at a glance
- COX inhibition → analgesic/anti-inflammatory
Safety / monitoring
- Celecoxib: less GI injury; CV/renal risk remains
- Ketorolac: potent, short-term only
Clinical role
- Acute musculoskeletal/inflammatory pain
- Can raise BP + worsen edema/heart failure
- Aspirin is unique for antiplatelet use
Safety distinctions
- GI ulcer/bleeding + renal injury are key risks
- Avoid stacking multiple NSAIDs
Self-check
- What clinically distinguishes Ketorolac within NSAIDs?
potent, short-term only.
Drugs in this class (24)
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