Antibacterials (cell-wall active)

Class at a glance

• Disrupt bacterial cell-wall synthesis

Practical pearls

• Includes beta-lactams + glycopeptides

Members / distinctions

• Often bactericidal
• Activity depends on organism + resistance

Other member distinctions

• Allergy, kidney effects + C. difficile matter
• Beta-lactam efficacy is time-above-MIC driven

Self-check

• Which major drug groups are included in Antibacterials (cell-wall active)?
  beta-lactams + glycopeptides.
• What is the main pharmacologic action of Antibacterials (cell-wall active)?
  Disrupt bacterial cell-wall synthesis.

Drugs in this class (31)

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