Not available in the U.S.
Cloxacillin
CLOXAPEN
“Clocks a’ ceiling”
Β lactam ring → the defining structure of penicillins and cephalosporins
What it isPenicillinase-resistant penicillin; staphylococcal infection outside the US.
Why this oneCovers MSSA where plain penicillin fails, and is the standard agent in many countries.
What limits itNo MRSA cover. Frequent dosing on an empty stomach; not US-marketed.
Cloxacillin prescription history
Animated chart of estimated U.S. prescriptions per year, Penicillins (oral) (1955–2026). Cloxacillin enters in 1963 (estimated).
FDA-approved for
- staphylococcal infections (1965)
NO BOXED WARNINGS
Principal riskNo MRSA cover
Classes and tags
Clinical profile
Open Cloxacillin in the interactive console ↗
Memory aids: interaction avatars
Open Cloxacillin in the interactive console ↗
Self-check
- Does cloxacillin cover MRSA?
No. - How should cloxacillin be taken relative to meals?
On an empty stomach.