Atherosclerotic cardiovascular disease (ASCVD) — risk reduction
- Statin is the lipid-lowering foundation
- High-risk disease usually warrants intensive LDL lowering
- Add ezetimibe/PCSK9 therapy if LDL remains above goal
- Control BP, diabetes, smoking + activity
- Antiplatelet therapy for appropriate secondary prevention
- Treat overall risk—not LDL alone
Use at a glance
- Statin is the lipid-lowering foundation
Treatment options
- Control BP, diabetes, smoking + activity
- Antiplatelet therapy for appropriate secondary prevention
Choosing treatment
- Add ezetimibe/PCSK9 therapy if LDL remains above goal
Practical pearls
- High-risk disease usually warrants intensive LDL lowering
- Treat overall risk—not LDL alone
Self-check
- What is the lipid-lowering foundation of ASCVD risk reduction?
A statin.
- When is antiplatelet therapy used in ASCVD prevention?
Appropriate secondary prevention.
Drugs used for this (5)
All clinical uses · Open the interactive console ↗
