Atherosclerotic cardiovascular disease (ASCVD) — risk reduction
- Statin is the lipid-lowering foundation
- High-risk disease usually warrants intensive LDL lowering
- Add ezetimibe/PCSK9 therapy if LDL remains above goal
- Control BP, diabetes, smoking + activity
- Antiplatelet therapy for appropriate secondary prevention
- Treat overall risk—not LDL alone
Use at a glance
- Statin is the lipid-lowering foundation
Treatment options
- Control BP, diabetes, smoking + activity
- Antiplatelet therapy for appropriate secondary prevention
Choosing treatment
- Add ezetimibe/PCSK9 therapy if LDL remains above goal
Practical pearls
- High-risk disease usually warrants intensive LDL lowering
- Treat overall risk—not LDL alone
Self-check
- What anchors ASCVD lipid lowering?
A statin. - When is antiplatelet therapy used in ASCVD prevention?
Appropriate secondary prevention.
Drugs used for this (15)
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