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Fluvoxamine CR

LUVOX CR

What it isControlled-release serotonin-reuptake inhibitor and sigma-1 agonist; OCD and social anxiety disorder.

Why this oneIt is taken once nightly, and the CR label adds social anxiety disorder to OCD.

What limits itPotent CYP1A2 inhibition makes caffeine, clozapine, and tizanidine interactions clinically important; nausea and sexual effects remain.

FDA-approved for

⚠ BOXED WARNING

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

Mechanism of action: Fluvoxamine CR ballicule

Fluvoxamine CR ballicule: receptor binding, kinetics and half-life diagram

Open Fluvoxamine CR in the interactive console ↗

Memory aids: mascots and interaction avatars

Fluvoxamine CR LUVOX mascot mnemonic cartoon
“gLove-ox man”
Sterile glove → for OCD
Fluffer inHibitor (fluoxetine, fluvoxamine, fluconazole)
Fluvoxamine CR CYP1A2 inhibitor avatar
CYP1A2 inhibitor (strong)
Fluvoxamine CR CYP2C19 inhibitor avatar
CYP2C19 inhibitor (strong)
Fluvoxamine CR CYP3A4 inhibitor avatar
CYP3A4 inhibitor (moderate — sources disagree)

Open Fluvoxamine CR in the interactive console ↗