Synthetic analogs of endogenous compounds

Class at a glance

• Synthetic drugs modeled on endogenous ligands

Pharmacology

• Structural relation—not one mechanism

Practical pearls

• Analogs may alter potency, selectivity + half-life

Other practical pearls

• Browse relationship is explicitly stored

Self-check

• What properties may synthetic analogs change?
  Potency, selectivity and half-life.
• Does structural relationship to an endogenous ligand define one mechanism?
  No.

Drugs in this class (18)

All drug classes · Open Synthetic analogs of endogenous compounds in the interactive console ↗