Endogenous neurotransmitters (monoamine)
- Dopamine, norepinephrine, serotonin + histamine
- Synthesized enzymatically from amino acids
- GPCR signaling predominates
- Transporters + MAO/COMT terminate signaling
- Core targets of many psychotropics
- Effects depend on pathway and receptor subtype
Class at a glance
- Dopamine, norepinephrine, serotonin + histamine
Pharmacology
- Transporters + MAO/COMT terminate signaling
- Effects depend on pathway and receptor subtype
Practical pearls
- Synthesized enzymatically from amino acids
Other practical pearls
- GPCR signaling predominates
- Core targets of many psychotropics
Drugs in this class (5)
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