Serotonin
5-HT
What it isThe endogenous ligand at fourteen receptor subtypes plus SERT.
Why it mattersAlmost every psychiatric and antiemetic drug class is positioned by which subtype it engages.
What it changesIt does not cross the blood-brain barrier, so peripheral and central serotonin are effectively separate systems.
NO BOXED WARNINGS
Principal riskEndogenous or dietary; no boxed warning applies
Classes and tags
Clinical profile
Mechanism of action: Serotonin ballicule
