Antifungals

Class at a glance

• Choice depends on organism + infection site

Members / distinctions

• Azoles: broad oral/systemic options
• Echinocandins: invasive Candida workhorses
• Amphotericin: broad but toxic rescue therapy
• Terbinafine: dermatophyte/onychomycosis niche

Practical pearls

• Species/susceptibility can dictate therapy

Safety / monitoring

• Hepatic, renal + QT toxicities vary greatly

Self-check

• What is the key clinical organizing principle for Antifungals?
  Choice depends on organism + infection site.

Drugs in this class (16)

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