Antifungals
- Choice depends on organism + infection site
- Azoles: broad oral/systemic options
- Echinocandins: invasive Candida workhorses
- Amphotericin: broad but toxic rescue therapy
- Terbinafine: dermatophyte/onychomycosis niche
- Hepatic, renal + QT toxicities vary greatly
- Species/susceptibility can dictate therapy
Class at a glance
- Choice depends on organism + infection site
Members / distinctions
- Azoles: broad oral/systemic options
- Echinocandins: invasive Candida workhorses
- Amphotericin: broad but toxic rescue therapy
- Terbinafine: dermatophyte/onychomycosis niche
Practical pearls
- Species/susceptibility can dictate therapy
Safety / monitoring
- Hepatic, renal + QT toxicities vary greatly
Self-check
- What distinguishes Antifungals?
Choice depends on organism + infection site.
- Which antifungal class is a workhorse for invasive Candida?
Echinocandins.
Drugs in this class (16)
Antifungals prescription history
Animated chart of estimated U.S. prescriptions per year, Antifungals (1947–2026).
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