Schizophrenia
- Antipsychotic + psychosocial treatment
- Choose by prior response + adverse effects
- LAI if preferred or adherence is difficult
- 2 adequate drug failures → clozapine
- Clozapine also lowers recurrent suicide risk
- Avoid routine chronic polypharmacy
- Monitor metabolic effects, EPS + prolactin
Use at a glance
- Antipsychotic + psychosocial treatment
Treatment options
- Choose by prior response + adverse effects
- 2 adequate drug failures → clozapine
Choosing treatment
- LAI if preferred or adherence is difficult
Monitoring / follow-up
- Clozapine also lowers recurrent suicide risk
- Avoid routine chronic polypharmacy
- Monitor metabolic effects, EPS + prolactin
Self-check
- What should generally be avoided in Schizophrenia?
routine chronic polypharmacy.
- What factors should guide treatment choice for Schizophrenia?
prior response + adverse effects.
Drugs used for this (23)
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