Schizophrenia
- Antipsychotic + psychosocial treatment
- Choose by prior response + adverse effects
- LAI if preferred or adherence is difficult
- 2 adequate drug failures → clozapine
- Clozapine also lowers recurrent suicide risk
- Avoid routine chronic polypharmacy
- Monitor metabolic effects, EPS + prolactin
Use at a glance
- Antipsychotic + psychosocial treatment
Treatment options
- Choose by prior response + adverse effects
- 2 adequate drug failures → clozapine
Choosing treatment
- LAI if preferred or adherence is difficult
Monitoring / follow-up
- Clozapine also lowers recurrent suicide risk
- Avoid routine chronic polypharmacy
- Monitor metabolic effects, EPS + prolactin
Self-check
- Which chronic prescribing pattern is avoided in schizophrenia?
Routine chronic polypharmacy. - What guides schizophrenia drug choice?
Prior response + adverse effects.
Drugs used for this (24)
All clinical uses · Open Schizophrenia in the interactive console ↗