Motion sickness
- Antimuscarinic/H1 blockade works best before exposure
- Scopolamine patch is highly effective for prolonged risk
- Meclizine/dimenhydrinate are common alternatives
- Sedation and antimuscarinic effects are common
- Habituation/visual-horizon strategies can help
- 5-HT3 antagonists are generally poor motion-sickness drugs
Use at a glance
- Antimuscarinic/H1 blockade works best before exposure
Practical pearls
- Meclizine/dimenhydrinate are common alternatives
- Sedation and antimuscarinic effects are common
Treatment options
- Habituation/visual-horizon strategies can help
- 5-HT3 antagonists are generally poor motion-sickness drugs
Other practical pearls
- Scopolamine patch is highly effective for prolonged risk
Self-check
- What works best before motion-sickness exposure?
Antimuscarinic/H1 blockade. - Are 5-HT3 antagonists generally good motion-sickness drugs?
No.
Drugs used for this (3)
All clinical uses · Open Motion sickness in the interactive console ↗