Helicobacter pylori eradication
- Treat every confirmed infection
- Empiric default: optimized bismuth quadruple
- PPI + bismuth + tetracycline + metronidazole
- Avoid clarithromycin unless susceptibility known
- Vonoprazan-based regimens are alternatives
- Confirm eradication after treatment
- Hold PPI before test-of-cure as directed
Use at a glance
- Treat every confirmed infection
Practical pearls
- Hold PPI before test-of-cure as directed
Treatment options
- Empiric default: optimized bismuth quadruple
- PPI + bismuth + tetracycline + metronidazole
- Vonoprazan-based regimens are alternatives
- Confirm eradication after treatment
Safety / pitfalls
- Avoid clarithromycin unless susceptibility known
Self-check
- What should follow H. pylori treatment?
Confirmation of eradication. - Which H. pylori antibiotic requires known susceptibility?
Clarithromycin.
Drugs used for this (6)
All clinical uses · Open Helicobacter pylori eradication in the interactive console ↗