Helicobacter pylori eradication
- Treat every confirmed infection
- Empiric default: optimized bismuth quadruple
- PPI + bismuth + tetracycline + metronidazole
- Avoid clarithromycin unless susceptibility known
- Vonoprazan-based regimens are alternatives
- Confirm eradication after treatment
- Hold PPI before test-of-cure as directed
Use at a glance
- Treat every confirmed infection
Practical pearls
- Hold PPI before test-of-cure as directed
Treatment options
- Empiric default: optimized bismuth quadruple
- PPI + bismuth + tetracycline + metronidazole
- Vonoprazan-based regimens are alternatives
- Confirm eradication after treatment
Safety / pitfalls
- Avoid clarithromycin unless susceptibility known
Self-check
- What should be treated in Helicobacter pylori eradication?
every confirmed infection.
- What should generally be avoided in Helicobacter pylori eradication?
clarithromycin unless susceptibility known.
Drugs used for this (6)
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