Precursor to metabolite: Loxapine to 7-OH loxapine
Loxapine is converted to 7-OH loxapine by CYP1A2 / CYP3A4.
The pair
- Loxapine — Mid-potency typical; an inhaled form treats agitation.
- 7-OH loxapine — Active metabolite of loxapine; more D2-potent than the parent.
Anything that inhibits or induces CYP1A2, CYP3A4 shifts the balance between Loxapine and 7-OH loxapine.
Loxapine · 7-OH loxapine · Open Loxapine in the interactive console ↗