Precursor to metabolite: Halazepam to Nordiazepam
Halazepam is converted to Nordiazepam by CYP3A4.
The pair
- Halazepam — Older benzodiazepine anxiolytic converted to long-acting nordiazepam; sedation, accumulation, and dependence limit use.
- Nordiazepam — Long-acting active metabolite of diazepam and several other benzodiazepines; accumulation can prolong sedation.
Anything that inhibits or induces CYP3A4 shifts the balance between Halazepam and Nordiazepam.
Halazepam · Nordiazepam · Open Halazepam in the interactive console ↗