Ototoxicity
- Can injure cochlear and/or vestibular function
- Hearing loss, tinnitus or disequilibrium may occur
- Risk often rises with dose and renal impairment
- Other ototoxins can add toxicity
- Damage may be irreversible
Interaction at a glance
- Can injure cochlear and/or vestibular function
Mechanism
- Can injure cochlear and/or vestibular function
- Hearing loss, tinnitus or disequilibrium may occur
- Damage may be irreversible
Clinical consequence
- Other ototoxins can add toxicity
Who is at greatest risk
- Risk often rises with dose and renal impairment
Self-check
- What is the main clinical risk of Ototoxicity?
Other ototoxins can add toxicity.
- How does Ototoxicity risk change as dose and renal impairment rises?
It increases.
Drugs in this interaction (11)
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