Ototoxicity
- Can injure cochlear and/or vestibular function
- Hearing loss, tinnitus or disequilibrium may occur
- Risk often rises with dose and renal impairment
- Other ototoxins can add toxicity
- Damage may be irreversible
Interaction at a glance
- Can injure cochlear and/or vestibular function
Mechanism
- Can injure cochlear and/or vestibular function
- Hearing loss, tinnitus or disequilibrium may occur
- Damage may be irreversible
Clinical consequence
- Other ototoxins can add toxicity
Who is at greatest risk
- Risk often rises with dose and renal impairment
Self-check
- Can ototoxic damage be permanent?
Yes; it may be irreversible. - How does ototoxicity risk often change with dose and renal impairment?
It rises.
Drugs in this interaction (11)
All interaction examples · Open Ototoxicity in the interactive console ↗