MAO-B inhibitor
- Inhibits monoamine oxidase B
- In brain, reduces dopamine breakdown
- Used mainly in Parkinson disease
- Selectivity can diminish at higher exposure
- Serotonin/tyramine risk rises if MAO-A is also inhibited
Interaction at a glance
- Inhibits monoamine oxidase B
Mechanism
- Inhibits monoamine oxidase B
- Used mainly in Parkinson disease
Magnitude / time course
- Selectivity can diminish at higher exposure
Clinical consequence
- Serotonin/tyramine risk rises if MAO-A is also inhibited
Management
- In brain, reduces dopamine breakdown
Self-check
- What does “MAO-B inhibitor” mean?
Inhibits monoamine oxidase B.
Drugs in this interaction (13)
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