Transdermal formulations

Class at a glance

• Drug delivered across skin

Practical pearls

• Usually provides slow sustained exposure

Members / distinctions

• Heat can increase delivery for some patches
• Patch disposal/skin reactions matter

Safety / monitoring

• Avoids GI absorption + much first-pass metabolism

Self-check

• What can heat do to delivery from some patches?
  Increase it.
• What exposure does transdermal delivery avoid?
  GI absorption and much first-pass metabolism.

Drugs in this class (18)

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