Status epilepticus
- Treat convulsive SE immediately
- 1st: adequate-dose benzodiazepine
- IV lorazepam; IM midazolam if no IV
- Then load a maintenance ASM promptly
- LEV, valproate or fosphenytoin
- Similar efficacy among those 3 options
- Refractory SE → ICU anesthetic + EEG
Use at a glance
- Treat convulsive SE immediately
Escalation / refractory disease
- Refractory SE → ICU anesthetic + EEG
Practical pearls
- Similar efficacy among those 3 options
Choosing treatment
- 1st: adequate-dose benzodiazepine
- IV lorazepam; IM midazolam if no IV
Other practical pearls
- Then load a maintenance ASM promptly
- LEV, valproate or fosphenytoin
Self-check
- What should be treated in Status epilepticus?
convulsive SE immediately.
- What is recommended for Refractory SE in Status epilepticus?
ICU anesthetic + EEG.
Drugs used for this (5)
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