Psychotic disorders

Antipsychotic medication is the pharmacologic core
Choose by efficacy, adverse effects + prior response
LAIs reduce relapse when adherence is a problem
Clozapine for treatment-resistant schizophrenia
Psychosocial rehabilitation is essential
Minimize chronic polypharmacy without a clear rationale

Use at a glance

Antipsychotic medication is the pharmacologic core

Treatment options

Choose by efficacy, adverse effects + prior response
Clozapine for treatment-resistant schizophrenia

Practical pearls

Psychosocial rehabilitation is essential
Minimize chronic polypharmacy without a clear rationale

Choosing treatment

LAIs reduce relapse when adherence is a problem

Self-check

What factors should guide treatment choice for Psychotic disorders?
efficacy, adverse effects + prior response.

Drugs used for this (23)

Quetiapine ballicule — decagon mechanism diagram — Quetiapine — off-label

Aripiprazole ballicule — decagon mechanism diagram — Aripiprazole — off-label

Risperidone ballicule — decagon mechanism diagram — Risperidone — off-label

Olanzapine ballicule — decagon mechanism diagram — Olanzapine — off-label

Haloperidol oral/IM ballicule — decagon mechanism diagram — Haloperidol oral/IM — off-label

Lurasidone ballicule — decagon mechanism diagram — Lurasidone — off-label

Ziprasidone ballicule — decagon mechanism diagram — Ziprasidone — off-label

Paliperidone ballicule — decagon mechanism diagram — Paliperidone — off-label

Cariprazine ballicule — decagon mechanism diagram — Cariprazine — off-label

Brexpiprazole ballicule — decagon mechanism diagram — Brexpiprazole — off-label

Chlorpromazine ballicule — decagon mechanism diagram — Chlorpromazine — off-label

Fluphenazine ballicule — decagon mechanism diagram — Fluphenazine — off-label

Perphenazine ballicule — decagon mechanism diagram — Perphenazine — off-label

Lumateperone ballicule — decagon mechanism diagram — Lumateperone — off-label

Asenapine ballicule — decagon mechanism diagram — Asenapine — off-label

Loxapine ballicule — decagon mechanism diagram — Loxapine — off-label

Iloperidone ballicule — decagon mechanism diagram — Iloperidone — off-label

Trifluoperazine ballicule — decagon mechanism diagram — Trifluoperazine — off-label

Thioridazine ballicule — decagon mechanism diagram — Thioridazine — off-label

Thiothixene ballicule — decagon mechanism diagram — Thiothixene — off-label

Molindone ballicule — decagon mechanism diagram — Molindone — off-label

Milsaperidone ballicule — decagon mechanism diagram — Milsaperidone — off-label

Xanomeline ballicule — decagon mechanism diagram — Xanomeline — off-label

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