Peptic ulcer disease (PUD)
- Eradicate H. pylori when present
- Stop NSAID or reduce exposure when possible
- PPI is the core acid-suppressive therapy
- Bleeding ulcer needs endoscopic hemostasis + high-dose PPI
- Confirm eradication after H. pylori treatment
- Refractory/recurrent ulcer requires cause review
Use at a glance
- Eradicate H. pylori when present
Escalation / refractory disease
- Refractory/recurrent ulcer requires cause review
Treatment options
- PPI is the core acid-suppressive therapy
- Bleeding ulcer needs endoscopic hemostasis + high-dose PPI
- Confirm eradication after H. pylori treatment
Choosing treatment
- Stop NSAID or reduce exposure when possible
Self-check
- What does a bleeding peptic ulcer require?
Endoscopic hemostasis + high-dose PPI. - What should be done with an ulcer-causing NSAID when possible?
Stop it or reduce exposure.
Drugs used for this (8)
All clinical uses · Open Peptic ulcer disease (PUD) in the interactive console ↗