Parkinson disease
- Levodopa is the most effective motor-symptom therapy
- Dopamine agonist/MAO-B inhibitor for selected patients
- Adjust dosing for wearing-off/dyskinesia
- DBS or infusion therapy for advanced fluctuations
- Exercise is a core nonpharmacologic treatment
- Treat psychosis, orthostasis + cognition separately
Use at a glance
- Levodopa is the most effective motor-symptom therapy
Choosing treatment
- Dopamine agonist/MAO-B inhibitor for selected patients
- Adjust dosing for wearing-off/dyskinesia
Treatment options
- DBS or infusion therapy for advanced fluctuations
Other treatment options
- Exercise is a core nonpharmacologic treatment
- Treat psychosis, orthostasis + cognition separately
Self-check
- What should be treated in Parkinson disease?
psychosis, orthostasis + cognition separately.
- What is used for advanced fluctuations in Parkinson disease?
DBS or infusion therapy.
Drugs used for this (17)
All clinical uses · Open the interactive console ↗