Pain (acute)
- Use multimodal nonopioid therapy first
- NSAID ± acetaminophen for many causes
- Local/regional therapy when feasible
- Opioid only when severity warrants
- lowest effective dose, shortest duration
- Suzetrigine = nonopioid NaV1.8 option
- Escalating pain → reassess the diagnosis
Use at a glance
- Use multimodal nonopioid therapy first
Choosing treatment
- Local/regional therapy when feasible
Practical pearls
- NSAID ± acetaminophen for many causes
- Suzetrigine = nonopioid NaV1.8 option
Treatment selection
- Opioid only when severity warrants
- lowest effective dose, shortest duration
Monitoring / follow-up
- Escalating pain → reassess the diagnosis
Self-check
- What comes first for acute pain?
Multimodal nonopioid therapy. - What should escalating acute pain prompt?
Reassessment of the diagnosis.
Drugs used for this (12)
All clinical uses · Open Pain (acute) in the interactive console ↗