Irritable bowel syndrome with diarrhea (IBS-D)
- Diet + trigger management first
- Loperamide helps diarrhea, not global IBS pain
- Rifaximin treats global IBS-D symptoms
- Eluxadoline for selected patients
- Low-dose TCA can reduce pain/diarrhea
- Avoid eluxadoline without gallbladder
- Evaluate alarm features before labeling IBS
Use at a glance
- Diet + trigger management first
Practical pearls
- Evaluate alarm features before labeling IBS
Other practical pearls
- Loperamide helps diarrhea, not global IBS pain
- Rifaximin treats global IBS-D symptoms
- Low-dose TCA can reduce pain/diarrhea
Choosing treatment
- Eluxadoline for selected patients
Safety / pitfalls
- Avoid eluxadoline without gallbladder
Self-check
- Which IBS-D drug is avoided without a gallbladder?
Eluxadoline. - What comes first in IBS-D?
Diet + trigger management.
Drugs used for this (8)
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