Precursor to metabolite: Temsirolimus to Sirolimus

Temsirolimus is converted to Sirolimus by esterase.

Sirolimus mascot — mnemonic cartoon — Sirolimus — mascot

The pair

Temsirolimus — IV mTOR inhibitor for renal cell carcinoma; converts to sirolimus.
Sirolimus — mTOR inhibitor immunosuppressant (rapamycin).

Temsirolimus · Sirolimus · Open Temsirolimus in the interactive console ↗